Study of the retention behaviour of monofluorinated analogues of Polybrominated Diphenylethers (F-PBDEs) in gas chromatography
نویسندگان
چکیده
Introduction Polybrominated diphenyl ethers (PBDEs) are globally distributed in the environment. They have been used as flame retardants for over 2 decades [1]. PBDEs have been found to bioaccumulate and there is also a concern about the health effects of PBDE exposure due to their potential endocrine disrupting properties. PBDEs are structurally similar to polychlorinated biphenyls (PCBs) and tend to concentrate in the lipid tissue. This has lead to extensive monitoring of PBDEs in all environmental matrices. The sample preparation and instrumental determination may lead to systematic and non-systematic (random) errors. It is generally accepted that the accurate determination of micro contaminants in such complex mixtures requires the use of internal standards (ISs). The benefit of using ISs with physico-chemical properties similar to those of the target compounds, is that both systematic and random errors will be minimized. Preliminary work on monofluorinated polycyclic aromatic hydrocarbons (F-PAHs) as ISs in gas chromatography (GC) is very promising [2], and therefore monofluorinated polybrominated diphenylethers (F-PBDE were synthesized [3] to determine if they could also be used as internal standards. F-PBDEs can be uses as internal standards for trace-level analysis of PBDEs and are alternatives to C-labelled analogues. The present study focused on the retention behavior of FPBDEs in GC, with the intention to use them as calibration standards for electron impact mass spectrometry (EI-MS) and GC-MS in the negative chemical ionisation mode (ECNI) GC-ECNIMS. Selected F-PBDEs can also be used as internal standards with GC-Electron Capture Detection (GC-ECD)
منابع مشابه
Monofluorinated analogues of polybrominated diphenylethers (F-PBDEs) - standards for analysis: retention behaviour in gas chromatography
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